Host–Pathogen Interactions: Proline Gives Insect Pathogens the Green Light

نویسنده

  • Nick Waterfield
چکیده

How does a quiescent symbiont of a nematode worm know when to turn nasty? Metabolic analysis and genetic knockouts confirm that model insect pathogens can sense L-proline in insect blood. This not only serves as a wake-up call, activating secondary metabolite virulence factors, but also provides an energy source for a metabolic shift appropriate for adaptation to the host environment.

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عنوان ژورنال:
  • Current Biology

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2010